1. This tiny website was prepared by the students of the OpenUniversity, as the partial fulfillment of the requirements of the seminary in applied biotechnology. Should anyone believe his copyrights have been violated, he may apply to

and specify the word Abuse17 in the subject so that his email could penetrate our spam filter. The offending text will be removed.

2. Some parts of this page might seem to be copied from Wikipedia. This is incorrect. The corresponding Wikipedia article was originally written by Dr AbuAmir, hence the similarity...

<a href="http://www.fermentek.co.il/geldanamycin.htm">&nbsp;

cnt

17-DMAG

Description

17-(Dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG, NSC 707545) is the first water-soluble analogue of 17-AAG. This Hsp90 inhibitor shows promise in preclinical models. 17-DMAG has excellent bioavailability, is widely distributed to tissues, and is quantitatively metabolized much less than is 17-AAG.

Formula: C₃₂H₄₈N₄O₈, HCl

Molecular weight: 652

The USA government claimed rights on 17-DMAG; see   United States Patent 6,890,917 Snader ,   et al. May 10, 2005. It is remarkable that none of the producers and resellers of 17DMAG declare they have license to make it.

Geldanamycin derivated at the 17^th position to yield 17aag

 

 

 

 

Geldanamycin derivated at the 17^th position to yield 17DMAG